A 42-year-old woman presents to the endocrine clinic with weight gain, hypertension and impaired glucose tolerance. Over the past year she has gained 8 kg in weight. Other symptoms include heightened libido and increased hair growth on the lower abdomen and upper chest. On examination her BP is 162/95 mmHg, pulse is 68 and regular. She has a BMI of 32 and abdominal striae. Investigations show: Haemoglobin 10.5 g/dl(11.5-16.0) White cell count 8.0 x 109/L (4-11) Platelets 205 x 109/L (150-400) Sodium 138 mmol/l (135-146) Potassium 3.9 mmol/l (3.5-5) Creatinine 123 μmol/l (79-118) Alkaline phosphatase 240 U/l (39-117) Alanine aminotransferase 190 U/l (5-40) Overnight dexamethasone suppression test positive Which of the following is the most likely diagnosis? 1- Adrenal adenoma 2- Adrenal carcinoma 3- Pituitary adenoma 4- Pseudo-Cushings 5- Simple obesity
Posted on: Fri, 04 Jul 2014 08:52:52 +0000