ANSWER TO LAST WEEKS QUIZ: Answer: C The image shows a - TopicsExpress

ANSWER TO LAST WEEKS QUIZ: Answer: C The image shows a glomerulus with endocapillary and mesangial hypercellularity with mildly expanded mesangial matrix. The H&E image demonstrates highly eosinophilic, discontinuous, ribbon-like thickening of the glomerular capillary loops, raising the possibility of DDD. Although post-infectious glomerulonephritis might share the same clinical presentation with DDD, it lacks the presence of ribbon-like, thickened capillary loops. The diagnosis of DDD, would be further confirmed by the dominant C3 staining on immunofluorescence and the presence of highly electron dense, intramembranous deposits on EM. Lupus nephritis can show hyaline, glassy thickened capillary loops (Wire-Loop), but the negative serology in this case makes this possibility less likely.

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