Answer: Q3) In erythroid cell, excess iron binds to which of the following to form ferritin? a) Apoferritin b) Transferritin c) Coferritin d) Endoferritin Correct Answer: a) Apoferritin. Free iron is toxic to cells as it acts as a catalyst in the formation of free radicals from reactive oxygen species via the Fenton Reaction. Hence vertebrates evolve an elaborate set of protective mechanisms to bind iron in various tissue compartments. Within cells, iron is stored in a protein complex as ferritin or hemosiderin. Apoferritin binds to free ferrous iron and stores it in the ferric state.
Posted on: Sun, 25 Jan 2015 03:36:00 +0000
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