Answer to yesterday’s quiz: In which one of the following scenarios would treatment with antibiotics most likely be indicated? A. Suspected food poisoning. B. Mild diarrhea caused by salmonella. C. Shiga toxin–producing E. coli infection. D. Shigellosis. The answer is D. Shigella typically causes acute febrile dysentery and should be treated with ciprofloxacin or azithromycin. Noroviruses are the most common pathogens in diarrhea due to foodborne infection, and in most cases of food poisoning that are not severe, empirical antibiotics are not indicated. Currently, antibiotic therapy is not helpful in cases of mild diarrhea caused by salmonella, and it lengthens shedding for 3 weeks or longer. Some antibiotics induce Shiga toxin–encoding phage and may precipitate the hemolytic–uremic syndrome. Therefore, in an outbreak of bloody diarrhea, antibiotics are not currently recommended for patients with minimal or no fever who have Shiga toxin–producing E. coli infection. nej.md/1nqpwsH
Posted on: Tue, 22 Apr 2014 14:00:01 +0000
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