By producing proteins that nurture cancer, tumor blood vessel cells can turn a slow-growing malignancy into an aggressive disease that can spread and resist treatment, Dr. Shahin Rafii and colleagues report in Cancer Cell. The researchers also found the crucial nurturing molecules that cancer co-opts from tumor blood vessels to promote invasiveness and resistance to chemotherapy. They show in animal experiments that shutting down these previously unrecognized biological signals makes cancer less aggressive and improves survival. bit.ly/1iDvSnP
Posted on: Wed, 19 Mar 2014 18:12:28 +0000