(CAUTION: NOT FOR THE FAINT AT HEART!!!) The company I work for is doing drug development to cure this disease; Critical Limb Ischemia. The condition is very prevalent in Third World Countries. Critical limb ischemia (CLI) is a severe blockage in the arteries of the lower extremities, which markedly reduces blood-flow. It is a serious form of peripheral arterial disease, or PAD, but less common than claudication. PAD is caused by atherosclerosis, the hardening and narrowing of the arteries over time due to the buildup of fatty deposits called plaque. CLI is a chronic condition that results in severe pain in the feet or toes, even while resting. Complications of poor circulation can include sores and wounds that wont heal in the legs and feet. Left untreated, the complications of CLI will result in amputation of the affected limb. SYMPTOMS The most prominent features of critical limb ischemia (CLI) are called ischemic rest pain — severe pain in the legs and feet while a person is not moving, or non-healing sores on the feet or legs. Pain or numbness in the feet Shiny, smooth, dry skin of the legs or feet Thickening of the toenails Absent or diminished pulse in the legs or feet Open sores, skin infections or ulcers that will not heal Dry gangrene (dry, black skin) of the legs or feet (because medical advancements are not everywhere, like here in the United States, the magets are added to eat away the dead flesh in hopes of improving the condition for the person)
Posted on: Sat, 13 Dec 2014 21:34:16 +0000
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