Cancer types: Non-small cell lung cancer and anaplastic large cell lymphoma Tissue analyzed: Tumor How used: To help determine treatment and prognosis Alpha-fetoprotein (AFP) Cancer types: Liver cancer and germ cell tumors Tissue analyzed: Blood How used: To help diagnose liver cancer and follow response to treatment; to assess stage, prognosis, and response to treatment of germ cell tumors Beta-2-microglobulin (B2M) Cancer types: Multiple myeloma, chronic lymphocytic leukemia, and some lymphomas Tissue analyzed: Blood, urine, or cerebrospinal fluid How used: To determine prognosis and follow response to treatment Beta-human chorionic gonadotropin (Beta-hCG) Cancer types: Choriocarcinoma and testicular cancer Tissue analyzed: Urine or blood How used: To assess stage, prognosis, and response to treatment BCR-ABL fusion gene Cancer type: Chronic myeloid leukemia Tissue analyzed: Blood and/or bone marrow How used: To confirm diagnosis and monitor disease status BRAF mutation V600E Cancer types: Cutaneous melanoma and colorectal cancer Tissue analyzed: Tumor How used: To predict response to targeted therapies CA15-3/CA27.29 Cancer type: Breast cancer Tissue analyzed: Blood How used: To assess whether treatment is working or disease has recurred CA19-9 Cancer types: Pancreatic cancer, gallbladder cancer, bile duct cancer, and gastric cancer Tissue analyzed: Blood How used: To assess whether treatment is working CA-125 Cancer type: Ovarian cancer Tissue analyzed: Blood How used: To help in diagnosis, assessment of response to treatment, and evaluation of recurrence Calcitonin Cancer type: Medullary thyroid cancer Tissue analyzed: Blood How used: To aid in diagnosis, check whether treatment is working, and assess recurrence Carcinoembryonic antigen (CEA) Cancer types: Colorectal cancer and breast cancer Tissue analyzed: Blood How used: To check whether colorectal cancer has spread; to look for breast cancer recurrence and assess response to treatment CD20 Cancer type: Non-Hodgkin lymphoma Tissue analyzed: Blood How used: To determine whether treatment with a targeted therapy is appropriate Chromogranin A (CgA) Cancer type: Neuroendocrine tumors Tissue analyzed: Blood How used: To help in diagnosis, assessment of treatment response, and evaluation of recurrence Chromosomes 3, 7, 17, and 9p21 Cancer type: Bladder cancer Tissue analyzed: Urine How used: To help in monitoring for tumor recurrence Cytokeratin fragments 21-1 Cancer type: Lung cancer Tissue analyzed: Blood How used: To help in monitoring for recurrence EGFR mutation analysis Cancer type: Non-small cell lung cancer Tissue analyzed: Tumor How used: To help determine treatment and prognosis Estrogen receptor (ER)/progesterone receptor (PR) Cancer type: Breast cancer Tissue analyzed: Tumor How used: To determine whether treatment with hormonal therapy (such as tamoxifen) is appropriate Fibrin/fibrinogen Cancer type: Bladder cancer Tissue analyzed: Urine How used: To monitor progression and response to treatment HE4 Cancer type: Ovarian cancer Tissue analyzed: Blood How used: To assess disease progression and monitor for recurrence HER2/neu Cancer types: Breast cancer, gastric cancer, and esophageal cancer Tissue analyzed: Tumor How used: To determine whether treatment with trastuzumab is appropriate Immunoglobulins Cancer types: Multiple myeloma and Waldenström macroglobulinemia Tissue analyzed: Blood and urine How used: To help diagnose disease, assess response to treatment, and look for recurrence KIT Cancer types: Gastrointestinal stromal tumor and mucosal melanoma Tissue analyzed: Tumor How used: To help in diagnosing and determining treatment KRAS mutation analysis Cancer types: Colorectal cancer and non-small cell lung cancer Tissue analyzed: Tumor How used: To determine whether treatment with a particular type of targeted therapy is appropriate Lactate dehydrogenase Cancer type: Germ cell tumors Tissue analyzed: Blood How used: To assess stage, prognosis, and response to treatment Nuclear matrix protein 22 Cancer type: Bladder cancer Tissue analyzed: Urine How used: To monitor response to treatment Prostate-specific antigen (PSA) Cancer type: Prostate cancer Tissue analyzed: Blood How used: To help in diagnosis, assess response to treatment, and look for recurrence Thyroglobulin Cancer type: Thyroid cancer Tissue analyzed: Tumor How used: To evaluate response to treatment and look for recurrence Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor (PAI-1) Cancer type: Breast cancer Tissue analyzed: Tumor How used: To determine aggressiveness of cancer and guide treatment 5-Protein signature (Ova1) Cancer type: Ovarian cancer Tissue analyzed: Blood How used: To pre-operatively assess pelvic mass for suspected ovarian cancer 21-Gene signature (Oncotype DX) Cancer type: Breast cancer Tissue analyzed: Tumor How used: To evaluate risk of recurrence 70-Gene signature (Mammaprint) Cancer type: Breast cancer Tissue analyzed: Tumor How used: To evaluate risk of recurrence
Posted on: Thu, 26 Sep 2013 17:06:05 +0000
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