Combinado con CoQ 10, Acetil L- Carnitine, Benfotiamina y otros nutrientes que intervienen positivamente en la Mitocondria, el PPQ tiene el potencial de multiplicar los efectos regeneradores de las células y evitar en lo más posible, el efecto oxidativo de las radicales libres. "PQQ activates expression of PCG-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a “master regulator” that mobilizes cells’ response to various external triggers. It directly stimulates genes that promote mitochondrial and cellular respiration, growth, and proliferation. Its capacity to upregulate cellular metabolism at the genetic level favorably affects blood pressure, cholesterol and triglyceride breakdown, and the onset of obesity.[13] PQQ triggers the CREB signaling protein (cAMP-response element-binding protein), which plays a pivotal role in embryonic development and growth. It also beneficially interacts with histones, proteins involved in the packaging and nuclear organization of cell DNA.[14] CREB also stimulates the growth of new mitochondria. PQQ regulates a recently discovered cell signaling protein called DJ-1. As with PCG-1α and CREB, DJ-1 is involved in cell function and survival, has been shown to prevent cell death by combating intensive oxidative stress,[15][16] and is likely important to brain health and function. DJ-1 mutations have been conclusively linked to the onset of rare inherited forms of Parkinson’s disease and other neurological disorders." en.wikipedia.org/wiki/Pyrroloquinoline_quinone
Posted on: Thu, 22 Aug 2013 01:22:00 +0000
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