Diabetes Drug Metformin Safe for Patients With Kidney Disease: Review JAMA 23/12/2014 After reviewing published research to evaluate the risks associated with metformin among people with mild to moderate kidney disease, A team of researchers led by Dr. Silvio Inzucchi, a professor of medicine at Yale University, found these patients were at no greater risk for lactic acidosis than people who were not taking the drug. The drug could be used safely, so long as kidney function is stable and not severely impaired, he said. The study authors pointed out: 1-their research didnt involve patients with severe kidney disease. 2-patients with kidney disease would need to be more closely monitored if they were taking metformin. 3-dosage of the drug may also need to be adjusted, depending on patients level of kidney function. The researchers said they are petitioning the FDA to update its guidelines, to make metformin available to more than 2.5 million Americans with type 2 diabetes.
Posted on: Sat, 17 Jan 2015 05:08:31 +0000
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