Diagnosis of GASTROESOPHAGEAL REFLUX DISEASE (GERD) • Based - TopicsExpress

Diagnosis of GASTROESOPHAGEAL REFLUX DISEASE (GERD) • Based on history and empiric trial of PPI (Se & Sp: 78% & 54%) • EGD (Esophagogastroduodenoscopy) if failure to respond to BID PPI (Proton Pump Inhibitor) or ALARM FEATURES are present, like: dysphagia, odynophagia, vomiting, wt loss, Fe-deficiency anemia, + Faecal Occult Blood, palpable mass or adenopathy, age above 55 y • If diagnosis uncertain & EGD normal, do High Resolution Manometry with 24-h esophageal pH monitoring

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