EULAR Recommendations for RA Joint Imaging medscape/viewarticle/804236 Recommendation 1: When there is diagnostic doubt, CR, ultrasound or MRI can be used to improve the certainty of a diagnosis of RA above clinical criteria alone. Strength of recommendation: 9.1 (95% CI 8.6 to 9.6) Recommendation 2: The presence of inflammation seen with ultrasound or MRI can be used to predict the progression to clinical RA from undifferentiated inflammatory arthritis. Strength of recommendation: 7.9 (95% CI 6.7 to 9.0) Recommendation 3: Ultrasound and MRI are superior to clinical examination in the detection of joint inflammation; these techniques should be considered for a more accurate assessment of inflammation. Strength of recommendation: 8.7 (95% CI 7.8 to 9.7) Recommendation 4: CR of the hands and feet should be used as the initial imaging technique to detect damage. However, ultrasound and/or MRI should be considered if CR do not show damage and may be used to detect damage at an earlier time point (especially in early RA). Strength of recommendation: 9.0 (95% CI 8.4 to 9.6) Recommendation 5: MRI bone oedema is a strong independent predictor of subsequent radiographic progression in early RA and should be considered for use as a prognostic indicator. Joint inflammation (synovitis) detected by MRI or ultrasound as well as joint damage detected by CR, MRI or ultrasound can also be considered for the prediction of further joint damage. Strength of recommendation: 8.4 (95% CI 7.7 to 9.2) Recommendation 6: Inflammation seen on imaging may be more predictive of a therapeutic response than clinical features of disease activity; imaging may be used to predict response to treatment. Strength of recommendation: 7.8 (95% CI 6.7 to 8.8) Recommendation 7: Given the improved detection of inflammation by ultrasound and MRI than by clinical examination, they may be useful in monitoring disease activity. Strength of recommendation: 8.3 (95% CI 7.4 to 9.1) Recommendation 8: The periodic evaluation of joint damage, usually by radiographs of the hands and feet, should be considered. MRI (and possibly ultrasound) is more responsive to change in joint damage and can be used to monitor disease progression. Strength of recommendation: 7.8 (95% CI 6.8 to 8.9) Recommendation 9: Monitoring of functional instability of the cervical spine by lateral radiograph obtained in flexion and neutral should be performed in patients with clinical suspicion of cervical involvement. When the radiograph is positive or specific neurological symptoms and signs are present, MRI should be performed. Strength of recommendation: 9.4 (95% CI 8.9 to 9.8) Recommendation 10: Ultrasound and MRI can detect inflammation that predicts subsequent joint damage, even when clinical remission is present and can be used to assess persistent inflammation. Strength of recommendation: 8.8 (95% CI 8.0 to 9.6)
Posted on: Wed, 05 Jun 2013 15:05:21 +0000