Follow-up re friend in ICU (after open-heart surgery gone wrong): it seems to me I can see clear signs of sleep apnea on the bedside monitor display showing his "vital signs", and his son had suspected this for years (loud snoring, etc.). I put together this "tutorial" outline, which is relevant for "YOU" even if you do not have sleep apnea: https://en.wikipedia.org/wiki/C-PAP Just to review the basics: Inadequate sleep (short duration or poor quality) elevates levels of homocysteine: Elevated levels of homocysteine put one at risk for many things, including atrial fibrillation (afib): https://ncbi.nlm.nih.gov/pubmed/15389232 There is an explanation for how homocysteine can promote afib and consolidate it (by remodeling): https://ncbi.nlm.nih.gov/pubmed/19964086 Elevated levels of homocysteine predict poor response to treatment for afib: https://ncbi.nlm.nih.gov/pubmed/20145348 https://ncbi.nlm.nih.gov/pubmed/22944088 NAC (n-acetyl-cysteine) lowers homocysteine: https://ncbi.nlm.nih.gov/pubmed/22226754 https://ncbi.nlm.nih.gov/pubmed/18214123 https://ncbi.nlm.nih.gov/pubmed/16047265 https://ncbi.nlm.nih.gov/pubmed/12711838 [etc., etc.] Besides being a natural "sleep promoter" (produced best if one avoids bright light -- especially "bluish" light-- in the evening, and sleep in total darkness on a regular schedule), melatonin is also an important anti-oxidant anti-inflammatory agent IN EVERY CELL OF YOUR BODY. Melatonin also lowers homocysteine levels: https://ncbi.nlm.nih.gov/pubmed/19212006 https://ncbi.nlm.nih.gov/pubmed/17427950 https://ncbi.nlm.nih.gov/pubmed/16487076 See also (re melatonin remedy for injury by homocysteine): https://ncbi.nlm.nih.gov/pubmed/15882843 https://ncbi.nlm.nih.gov/pubmed/16213988 RELATED: folate deficiency https://ncbi.nlm.nih.gov/pubmed/16213988
Posted on: Mon, 29 Jul 2013 20:20:07 +0000
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