For 3 decades, standard treatment for tuberculosis has consisted of a complex 6-month regimen. Recent experiments with mouse models and promising phase 2 trials, however, seemed to indicate efficacy using shorter and simpler therapeutic regimens. Disappointingly, three phase 3 trials testing a shorter duration treatment including a fluoroquinolone failed to demonstrate noninferiority to standard treatment. ja.ma/12JdSVf
Posted on: Tue, 30 Dec 2014 15:00:10 +0000
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