From Microbiome Journal, Integrative analysis of the microbiome - TopicsExpress

From Microbiome Journal, Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface Abstract available only: Conclusions The results suggest that microbes are syntropic with mucosal metabolome composition and therefore may be the source of and/or dependent upon gut epithelial metabolites. The consistent relationship between inferred metagenomic function and assayed metabolites suggests that metagenomic composition is predictive to a reasonable degree of microbial community metabolite pools. The finding that certain metabolites strongly correlate with microbial community structure raises the possibility of targeting metabolites for monitoring and/or therapeutically manipulating microbial community function in IBD and other chronic diseases. microbiomejournal/content/1/1/17

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