In this example just one neuron is recorded for repeated stimulation with the same stimulus. This stimulus is a chirp-function, representative of a non-periodic time-varying stimulus. It is assumed that the neuron is sensitive to negative amplitudes and accordingly it exhibits higher (lower) reliability for local minima (maxima) of the chirp function. In order to better illustrate the gradual increase in clustering half the trials were left unaffected. As the amplitude of the chirp function varies so does the spike train synchrony of half of the trials, but due to the non-periodicity of the stimulus this is quite difficult to detect. Detection is facilitated by externally triggered averaging where the triggering is performed on common stimulus features, here the amplitude of the chirp function. As can be seen in the dissimilarity matrices and even better in the dendrogram, a decrease of this stimulus amplitude leads to the emergence of a spike train cluster consisting of the modulated spike trains which indicates their increase in reliability.
Posted on: Sat, 31 May 2014 21:06:59 +0000
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