Innovation 5391: Lost memories might be able to be restored, suggests research into marine snail, 2014. sciencedaily/releases/2014/12/141220104133.htm “New research indicates that lost memories can be restored, according to new research into a type of marine snail called Aplysia. The findings offer some hope for patients in the early stages of Alzheimers disease.” … “Long-term memory is not stored at the synapse … Thats a radical idea, but thats where the evidence leads. The nervous system appears to be able to regenerate lost synaptic connections. If you can restore the synaptic connections, the memory will come back.” … “Long-term memory is a function of the growth of new synaptic connections caused by the serotonin, said Glanzman, a member of UCLAs Brain Research Institute. As long-term memories are formed, the brain creates new proteins that are involved in making new synapses. If that process is disrupted -- for example by a concussion or other injury -- the proteins may not be synthesized and long-term memories cannot form. (This is why people cannot remember what happened moments before a concussion).” … “If you train an animal on a task, inhibit its ability to produce proteins immediately after training, and then test it 24 hours later, the animal doesnt remember the training … However, if you train an animal, wait 24 hours, and then inject a protein synthesis inhibitor in its brain, the animal shows perfectly good memory 24 hours later. In other words, once memories are formed, if you temporarily disrupt protein synthesis, it doesnt affect long-term memory.” … “That suggests that the memory is not in the synapses but somewhere else …We think its in the nucleus of the neurons. We havent proved that, though.
Posted on: Sun, 21 Dec 2014 17:52:21 +0000
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