... It is possible that when very large doses of the drug are used, these organisms may be completely destroyed, but it is certain that in other cases, where complete healing of the lesions is accomplished as a result of treatment, the organisms are not destroyed. Moreover, it appears that such a result can be accomplished in the presence of numerous actively motile spirochetes, and once the effect of the drug has reached this point, either the capacity of the spirochetes for stimulating reaction on the part of the tissues is lowered or else the reactivity of the tissues is reduced. At any rate., living spirochetes may remain in the tissues for considerable periods of time without giving rise to the usual tissue reaction which characterizes these infections. ncbi.nlm.nih.gov/pubmed/19868372
Posted on: Sat, 22 Nov 2014 20:14:03 +0000
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