It looks like there is a good Kopriva Seminar TODAY... Dr. - TopicsExpress



          

It looks like there is a good Kopriva Seminar TODAY... Dr. Blake Wiedenheft, Assistant Professor Department of Immunology & Infectious Diseases Date: Tuesday, November 12, 2013 Time: 4 PM Place: Procrastinator Theater, Strand Union Building Title: A CRISPR Immune Response to Viruses that Infect Bacteria Summary: Viruses that infect bacteria are the most diverse and abundant biological agents on the planet. In response to these pervasive viral predators, bacteria have evolved sophisticated adaptive immune systems that rely on Clusters of Regularly Interspersed Palindromic Repeats (CRISPRs). These repetitive elements rapidly expand in response to viral challenge by site-specifically integrating short fragments of the foreign DNA at one end of the evolving CRISPR. Small RNAs derived from CRISPR loci serve as guides that target nucleases to invading DNA targets. Our work aims to understand how these immune systems efficiently find and destroy DNA targets, and how they can be implemented as tools for human genome engineering.
Posted on: Tue, 12 Nov 2013 16:39:32 +0000

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