Kinesin motor proteins - amazing cargo carriers in the cell elshamah.heavenforum.org/t1448-kinesin-motor-proteins-amazing-cargo-carriers-in-the-cell The Kinesin motor protein is the cargo carrier in the cell and helps in cell division. Its lifes smallest motor. They look like a post man, marching and holding the cargo with two arms , almost like humans. They know exactly where to catch the cargo, where to go in the cell, and where to drop it. Micro tubule highways built up before they walk on them, assembled by proteins, each manufactured in accordance with the coded instructions of DNA, and once the cargo has been delivered at the right place, the nano highway dismantles. Until recently, scientists did not have a idea of how ATP fuel propels its walking like movement . The action happens at atomic level. That is one more example of the amazing engineering science has discovered in the cell. How do you want to explain these motors, which exist inside the cell ? They had all to be arise before life existed, since they make part of the cells functions. There is no selective advantage to have a half nanomotor. So how could it then arise in a step up fashion, just by natural means ? why should chance, physical necessity, or natural selection, provide a better explanation, than intelligent design ? youtube/watch?v=FJ4N0iSeR8U iaincarstairs.wordpress/2013/03/25/as-smart-as-molecules/ The kinesin illustrated above is from a Harvard animation and shows in correct proportion the transport of a sack of proteins from one place in the cell to another on one of the hundreds of thousands of highways which mysteriously build and unravel within every cell. Kinesin actually walks, step over step, travelling exclusively outwards from the centre of the cell, in strides of 8 nanometres. It can cope with obstacles in its path while holding onto its bag of goodies. It covers 1 millimetre in 125,000 steps, making at most a few hundred steps in each journey, at a rate of 100 steps/second. The 14 variant groups of these motor proteins have been the subject of ingenious research, some of which precisely measured their force in PicoNewtons while striding over nanometre bridges. The graph is a straight line, meaning they’re as strong at the end of the journey as the beginning: given a surrounding supply of ATP they are literally tireless. Kinesin’s fuel efficiency is nearly 50% – much more than a gasoline engine, and scaled up, exerts an incredible amount of torque. It requires no supernatural intervention: in vitro it behaves exactly as in the cell, given ATP, simply due to the arrangement of the amino acid components. Its step is precisely calibrated to the microtubule segments; the two components are part of one system. Therefore the distance walked by one of these little Santas in a day is 69 million nanometres, or 6.9 centimetres – small wonder you need your own body weight in ATP each day. Scale him up to our size so his stride is 80 cm rather than 8 Nm with a factor of 100m and he could be covering 4,200 miles in a day. With perhaps 100,000 at work in a single cell, and with 100 trillion cells, that’s a total distance travelled per day of just under 7 metres per cell, 691 billion km all told. Even if they only worked half the elapsed time, and then, only for one night – that’s easily enough to visit every house on the planet. As for the elves, hammering away – clearly a metaphor for the ribosomes! And Rudolph.. well, perhaps his nose is a phosphate molecule.
Posted on: Thu, 27 Nov 2014 01:54:44 +0000
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