Ktoś się domagał nowotworów dzisiaj. Cutaneous horn is a relatively uncommon lesion, also known by the Latin name “Cornu cutaneum.” It is conical hyperkeratotic projection above the surface of the skin that often resembles the horn of an animal. It may be straight or curved and twisted and vary from a few millimeters to several centimeters in length. The earliest documented case of cutaneous horn was that of an elderly Welsh woman in London who was displayed commercially as an anomaly of nature in 1588. There were several other accounts of cutaneous horns in the sixteenth and seventeenth centuries, including those described by Danish anatomist Thomas Bartholin in 1670. The London surgeons Everard Home and his brother-in-law John Hunter are generally credited with the characterization of cutaneous horns as a medical disorder in the late eighteenth century. (...) The important issue is not the horn itself which is dead keratin, but rather the underlying condition, which may be benign (seborrheic keratosis, viral warts, histiocytoma, inverted follicular keratosis, verrucous epidermal nevus, and molluscum contagiosum), premalignant (solar keratosis, arsenical keratosis, and Bowens disease), or malignant (squamous cell carcinoma, rarely, basal cell carcinoma, metastatic renal carcinoma, granular cell tumor, sebaceous carcinoma, or Kaposis sarcoma). Malignancy has been described in 16–20% of cases, with squamous cell carcinoma being the most common type. (...) Cutaneous horns are predominantly benign lesions; however possibility of nearly one third of them harboring malignant or premalignant skin lesions should be kept in mind. Full thickness excision with margin should be the treatment of choice to enable detailed pathological examination of the underlying tissue. ncbi.nlm.nih.gov/pmc/articles/PMC4123614/
Posted on: Mon, 03 Nov 2014 12:46:57 +0000
Trending Topics
Recently Viewed Topics
© 2015