Lipopolysaccharide assault (+) depletes liver copper and increases serum copper levels with potentially life-threatening / debilitating results While the copper loss in the liver will lower the apoptotic threshold (=it takes less for cells to die) and could induce necrosis, the increases of circulating copper might cause oxidative injury through Fenton reaction (oxidation) and contribute to tissue injury. suppversity (+) Lipopolysaccharides (LPS), also known as lipoglycans, are large molecules consisting of a lipid and a polysaccharide joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria, act as endotoxins and elicit strong immune responses in animals.
Posted on: Sun, 30 Jun 2013 10:02:15 +0000
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