Lisa is a 32-year-old, 50-kg woman recently given a diagnosis of - TopicsExpress

Lisa is a 32-year-old, 50-kg woman recently given a diagnosis of secondary hypothyroidism (HoTR) caused by idiopathic pan-hypopituitarism. She began treatment with levothyroxine 75 mcg orally once daily 2 weeks ago. The results of today’s thyroid function tests (TFTs) are as follows: total thyroxine (TT4) 4 mcg/dL (normal level [nl] 512), total triiodothyronine (TT3) 75 ng/dL (nl 80–180), and thyroid-stimulating hormone (TSH) less than 0.1 mIU/mL (nl 0.4–4.0). Given these laboratory tests, which is the best recommendation for Lisa’s T4 dose? A. Increase because triiodothyronine (T3) and thyroxine (T4) levels are low. B. Decrease because TSH levels are low. C. No change because free T4 levels are not available. D. No change because she has not yet reached steady state on this dose

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