Osteogenesis imperfecta Osteogenesis imperfecta is an inherited - TopicsExpress

Osteogenesis imperfecta Osteogenesis imperfecta is an inherited condition characterized by the fragility of the skeletal system and a susceptibility to fractures of the long bones or vertebral compressions. Osteogenesis imperfecta (OI) also called as brittle bone disease is the most common genetic cause of osteoporosis. Osteogenesis imperfecta is an autosomal dominant disorder that occurs in all racial and ethnic groups. The incidence of OI that is detectable in infancy is about 1 / 20, 000.

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