PERTUBATIONS IN THE HOMEOSTASIS OF ESSENTIAL MINERALS IN CHRONIC HEPATITIS C: A MODEL OF NUTRITION-VIRUS INTERACTION In conclusion, the concomitant presence of HCV infection and NAFLD results in more severe perturbations in the homeostasis of essential minerals (Zn, Se, and Cu) status, amplifying oxidative stress and inflammation. Such conditions may cause a low SVR to anti-HCV therapy. While the mechanism underlying the association between plasma minerals and NAFLD in patients with chronic hepatitis C is unknown, the development of NAFLD is a potential contributor to the disruption of homeostasis of these minerals. Improving the status of these minerals may thus alleviate the progression of NAFLD and increase SVR rates in patients with chronic hepatitis C.
Posted on: Wed, 19 Jun 2013 07:46:44 +0000