Primary tumor Because relapses often occur at the site of the - TopicsExpress



          

Primary tumor Because relapses often occur at the site of the original primary tumor, adequate local control is essential. Data from Europe suggest that chemotherapy alone can be effective for achieving adequate local control in some patients who have a complete response of the primary tumor. However, surgery and/or irradiation are needed for local control of residual disease. If possible, complete excision of the lesion should be performed with a wide (2-cm) margin of healthy tissue. Wide margins of normal tissue often are impossible to achieve at certain sites, such as the head and neck. If margins are narrow, obtain several biopsy specimens from the surrounding tissue to assess for residual local disease. For tumors that cannot be excised at diagnosis, a second-look procedure may be appropriate after a period of chemotherapy (usually 12 wk).
Posted on: Thu, 06 Mar 2014 13:56:47 +0000

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