TRIFEXIS and JoJo Potowski PLEASESHARE!!!! Pictures are before Trifexis and the day Jojo was euthanized after being given Trifexis. I. FIRST DOSE In early February of 2014 we gave a Trifexis pill to our three year old 12 pound Shih Tzu, JoJo. She took this Trifexis for the first time with her breakfast around 8 a.m. in the morning. Later the same day JoJo refused her dinner and she screamed in pain when picked up that same night by me. The morning after she took this first Trifexis she wretched a few times spitting up yellow bile. She was lethargic after being given this first Trifexis for a few days and then was back to normal. II. SECOND DOSE JoJo was given a Trifexis once again on March 9, 2014. She was given the pill with her breakfast at around 8 a.m. By dinner time she refused to eat and was very lethargic and had a slight fever. The morning after the Trifexis had been ingested she awoke to several bouts of wretching and vomiting up bright yellow bile (just like the month before). I picked JoJo up the first day after this second dose of Trifexis and she screamed in pain (just like the month before after taking the Trifexis)! I would describe her screams as startling, loud, screeches that penetrated your brain and heart each time she would let loose with a quick loud one. Since we had seen these same symptoms with the first dose of Trifexis the month before, we assumed that JoJo would snap out of it given a little time to do so. We were wrong in this assumption........this time JoJo never got any better. She acted continuously ill from the day she got the Trifexis and almost instantly withdrew from her place in our family. Her symptoms progressed a little each day or two after ingestion but we still hoped and wanted to believe that she would, given time, recover. She actually seemed to stay about the same over the course of day three till about day 5 or 6. This fueled our hope, She was clearly not feeling well but was holding her own, so to speak. On day 6, out of a growing concern, we contacted our Vet by phone to let him know of JoJos bad reaction to the Trifexis and to also see if they had heard of reactions like JoJos to the Trifexis. We also hoped there would be something he could recommend to do for her. The Vet denied any knowledge of any adverse reactions from Trifexis though his employee shared on the phone to my husband that she had personally decided not to give her own two dogs any more Trifexis because both of her dogs had vomited up their Trifexis pills each time given! Vet claimed he had never heard of similar bad reactions as JoJos, citing his own employees two dogs minor reactions to the Trifexis as the only problems he knew of with the product. He said we should make an appointment if we wanted him to take a look at her. We wanted to believe him that there was no info out there pointing to any problems with Trifexis and so we held out just a little more hope that whatever was happening to JoJo was not from an inherent problem with the Trifexis but from her own bodys immune system response to the chemicals and that her body would start to fight off the chemicals and these reactions would begin to wane and she would be okay. We began around day 7 or 8 to give her an aspirin to try and relieve her of some of the pain that was obvious in her walk and on her face. She didnt act like her pain was alleviated from taking an aspirin and because she vomited one of the aspirin up we discontinued giving that to her. Between day 6 and day 16 she got a little worse each day. One of the first symptoms I noticed was that she stopped holding her tail up and wagging it whenever she was talked to. After several days I knew that wagging her tail was painful and so this is why she stopped doing what came naturally. Then I noticed that she began holding herself in strange poses that we had never seen before.....nose/head in the air with arched back/abdomen, standing still for long periods of time in a trance-like state with her nose straight up in the air. From day one of ingesting the Trifexis she completely stopped ALL her normal daily routines (playing, greeting, leading, barking, guarding, jumping up, lying on laps, chasing Casper her schnauzer buddy, chewing on toys, fetching things). From about the third or fourth day her body began to have small tremors and twitches. The tremors began at her rear end and went down her two back legs. Over time the shakes moved along her backside all the way up to her head. So that, at the end when she was lying on the floor you could see her body twitching and shaking from her tail to her head. During this time she intermittently had bouts of rather significant strong abdominal twitching reminiscent of hiccups except only coming from the abdominal area (not the chest area like hiccups). She refused one of her two meals every day and by the end was not drinking water from her bowl on her own. We had to administer water by large dropper directly into her mouth in order for her to get any water at all. Because of pain she had to be carried up and down our one-step deck out back to go to potty. Each time we picked her up she would scream out so loudly it would assault our eardrums and we would wince and withdraw from her immediately so as not to hurt her any further. Her list of growing symptoms were guarding, flinching and jumping up at alert whenever someone would get up or move suddenly anywhere around her, screaming out not only at each movement of her own body but whenever someone would even barely touch her. In the end she was actually screaming out loud in anticipation of someone touching her (not actually touching her yet!). She also exhibited panting, hiding under furniture and in her crate, blood in her vomit (on day 13) signs of blindness, not picking up food (had to hand it to her), cessation of all grooming activities, cessation of all barking and generally reluctant to even move. At the end her tongue also became involved in that it would fall out of the side of her mouth and hang there a short time until she would pull it back into her mouth and she was licking her mouth almost constantly like there was something wrong with her mouth, tongue and/or throat. (By the way, there are adverse reaction reports that indicate that humans who have accidentally ingested Trifexis have complained of burning sensation in the throat.) On day 15, a Monday morning, I made the decision that we would have to subject little JoJo to more pain in order to get her looked at by the vet. Getting to the vet involved lifting her bodily into her cage in the back of our van and riding the long bumpy ride twenty miles to his office. She was in such a downward spiral and in such pain that we made an appointment for Tuesday afternoon to have our Vet take a look at JoJo and to bring him up to date on her level of pain and progressively worsening symptoms since the Trifexis. When we brought JoJo to the Vet on day 16, he could offer no natural supplements nor medicines to help alleviate the awful pain she was in and to help her recover.........so, we felt we had no other humane choice but to let her go. We put an end to her pain and suffering at approximately 3:15 p.m. on Tuesday March 25, 2014. On March 9, 2014 (at three years old) our pet was a perfectly healthy and extremely vibrant and unique little force of nature within our family. See attached picture. She was just simply the cutest, happiest, bounciest, happy-go-lucky little dog we have ever had the pleasure to know. On March 25, 2014 she was dead and gone! However, our little girl was actually taken from us the day she was given the Trifexis.......she was NEVER the same again. It just took us time to be able to comprehend that we had lost her and had to let her go. We are still in shock at the suddenness of losing the sunshine in our lives.
Posted on: Wed, 09 Jul 2014 14:54:34 +0000
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