Todays photo (Case 10) Infectious mononucleosis : Infectious mononucleosis also known as ( glandular fever ) is caused by Epstein Bar Virus (EBV) , which is transmitted by saliva , Incubation period is : 30- 45 days . Symptoms and Signs : Sore throat ,fever and malaise , Signs of exudative tonsilitis , lymphadenopathy and sometimes splenomegaly or a widespread maculopapular rash also treatment with ampicillin (for presumed streptococcal infection) also causes widespread maculopapular rash. Check for jaundice , and elevated liver enzymes for associated hepatitis . Diagnosis :(1) From the clinical picture (fever ,sore throat, rash ,lymhadenopathy, and splenomegaly. (2) Blood film : lymphocytosis with atypical lymphocytes (3) Positive monospot test (Paul -Bunnel ) for heterophile antibodies (4) If associated hepatitis there will be increased serum bilirubin and transaminases .(5) Specific tests for EBV are also positive ( EBV IgM) for recent infection . (Q) What are the possible complications of infectious monoculeosis ? (A) - Thrombocytopenia - Hemolytic anemia - Traumatic rupture of an enlarged spleen - Rarely Guillian Barre syndrome ,cerebellar ataxia ,aseptic meningitis ,encephalitis ,pneumonitis,pericarditis or lymphoma .
Posted on: Sun, 04 Jan 2015 18:00:40 +0000
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