Total normal brain and hippocampus volumes were directly - TopicsExpress

Total normal brain and hippocampus volumes were directly associated with levels of omega-3 fatty acids in a study of more than 1000 postmenopausal women. These results are consistent with the idea that higher omega-3 levels may slow the loss of brain volume that occurs as we age. Results showed that overall brain size was slightly but significantly smaller in the women in the lowest quartile of omega-3 index compared with those in the highest quartile. And specifically, the hippocampus, which is the area of the brain related to cognitive function, was also significantly smaller in the lowest vs the highest quartile of omega-3 index. This was after controlling for age, lipid levels, glucose, blood pressure, education, and hormone therapy. The hippocampal volume difference between the highest and lowest quartiles of omega-3 levels was about 2.5%. For comparison, other studies have shown that patients with fairly severe Alzheimers disease have hippocampus volumes about 40% smaller than people without dementia.

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