UpToDate Treatment of hypernatremiaより （高ナトリウム血症の治療） TBW refers to the estimated total body water, which is normally about 60 and 50 percent of lean body weight in younger men and women, respectively, and about 50 and 45 percent of lean body weight in elderly men and women, respectively [2]. However, it is probably reasonable to use values about 10 percent lower in hypernatremic patients who are water depleted. Of note, if the serum sodium is 141 meq/L and TBW is approximately 50 percent of lean body weight, then the water deficit is about 3 mL/kg. This provides the rationale for the estimation, mentioned above, that a net positive balance of 3 mL of electrolyte-free water per kilogram of lean body weight will lower the serum sodium by approximately 1 meq/L.
Posted on: Tue, 02 Dec 2014 07:41:36 +0000
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