#stopeb my little contribution to the #stopebchallenge . I want all my friends to take the challenge and raise awareness to this very little known painful disease that affects many children. For those who dont know what EB is: What is EB? Epidermolysis Bullosa (EB) is a group of genetic disorders that result in fragility of the skin and, in some cases, other internal membranes and organs. Blisters, open wounds and sores form as a result of the slightest touch, rub or trauma. Certain types of EB can be fatal in infancy and others are severely life-limiting. We estimate that there more than 5,000 people with EB in the UK, and 500,000 worldwide. EB may be inherited in either a dominant (usually one parent carries the gene for EB and is affected by the condition themselves) or a recessive form (where both parents carry the gene but are usually unaffected, so the birth of an affected child is totally unexpected). EB can also arise through a new spontaneous mutation whereby neither parent carries EB yet the gene mutates spontaneously in either the sperm or the egg before conception. In dominant EB, there is a 50% chance of passing the disorder to children: in recessive EB the chance is 25%. Rarely, a severe form of EB can be “acquired” as the result of autoimmune disease, whereby the body develops antibodies to its own tissue proteins. EB can be divided into 4 main types: Simplex, Dystrophic, Junctional and the recently classified Kindler Syndrome. There is currently no known cure for EB. Lisbey Garcia
Posted on: Mon, 01 Sep 2014 21:05:00 +0000
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