الفرق - TopicsExpress

الفرق بین...... parlodelﻭﺍﻝdostinex؟؟ ﻭلماذا ﺍﻝdostinexﺳﻌﺮﻩ ﻏﺎﻟﻲ هکذا ؟؟ (*)-ﺍﻭﻻ ﺍﻝparlodelیحتوي ﻋﻠﻰ bromocriptineﺑﺘﺮﻛﻴﺰ2.5mg والdostinex یحتويﻋﻠﻰcabergoline ﺑﺘﺮﻛﻴﺰmg .5 *ﺍﻝ2ﻋﺒﺎﺭﺓ ﻋﻦdopamine D2 agonist MOA....طریقة عملهم stimulation of dopamine D2 receptors in brain ﻓﻴﺆﺩﻭﺍ ﻟﺤﺪﻭﺙ blocking of prolactin receptorsﻓﻴﻘﻞ ﺗﺄﺛﻴﺮ ﻫﺮﻣﻮﻥ ﺍﻟﺒﺮﻭﻻﻛﺘﻴﻦ ﺣﺘﻰ ﻳﻨﺘﻬﻲ ﺍﻓﺮﺍﺯ ﺍﻟﻬﺮﻣﻮﻥ ﺗﻠﻘﺎﺋﻴﺎ -حسنا.... ما الذي یفرقهم عن بعض؟ شیئان:- -1ﺍﻥ ﺍﻝcabergolineﺍﻟﻤﻮﺟﻮﺩ ﻓﻲ ﺍﻝ dostinex) long acting D2 agonist( ﻟﻜﻦ ﺍﻝbromocriptineﺍﻟﻤﻮﺟﻮﺩ ﻓﻲ ﺍﻝ parlodel) short acting D2 agonist( یعني ذلگ أن جرعة ﺍﻝdostinex ستکون ﺍﻗﻞ ﻣﻦ ﺍﻝbromocriptine یعني ذلگ ﺍﻥ ﺍﻟﺠﺮﻋﺔ ﺍﻻﻗﻞ ستزید رغبة ﺍﻟﻤﺮﻳﺾ ﻟﻠﻌﻼﺝ ﻭﺍﻧﻪ ﻳﻠﺘﺰﻡ به ﻭﻟﺬﻟﻚ تجد ﺍﻝparlodel یحتوي ﻋﻠﻰ 2.5mgﻣﻦ ﺍﻝbromocriptine ﻭﺍﻝdostinex یحتوي فقط ﻋﻠﻰ ﻧﺺ ﻣﺠﻢ ﻣﻦ ﺍﻝcabergoline -2ﺍﻥ ﺍﻝcabergoline more selective ﻟﻞdopamine D2 receptorﻋﻦ ﺍﻝbromocriptineﺑﺎﻟﺘﺎﻟﻲ ﺍﻻﺛﺎﺭ ﺍﻟﺠﺎﻧﺒﻴﻪ ﺍﻟﻨﺎﺗﺠﺔ ﻋﻦ ﺍﻝdostinex ستکون ﺍﻗﻞ ﻣﻦ ﺍﻟذي سینتج ﻋﻦ ﺍﻝparlodelﻭﺍﺷﻬﺮﻫﺎ ﻃﺒﻌﺎ ﻣﺸﺎﻛﻞ ﺍﻝnausea & vomiting جرعة parlodel ﺟﺮﻋﺔ ﺍﻝparlodel؟؟ -ﻧﺺ ﻗﺮﺹ ﻣﺴﺎﺀﺍ ﻟﻤﺪﺓ ﻳﻮﻣﻴﻦ -ﻧﺺ ﻗﺮﺹ ﺻﺒﺎﺣﺎ ﻭﻧﺺ ﻗﺮﺹ ﻣﺴﺎﺀﺍ ﻟﻤﺪﺓ ﻳﻮﻣﻴﻦ -ﻧﺺ ﻗﺮﺹ ﺻﺒﺎﺣﺎ ﻭﻗﺮﺹ ﻣﺴﺎﺀﺍ ﻟﻤﺪﺓ ﻳﻮﻣﻴﻦ -ﻗﺮﺹ ﺻﺒﺎﺣﺎ ﻭﻗﺮﺹ ﻣﺴﺎﺀﺍ ﻟﻤﺪﺓ ﻳﻮﻣﻴﻦ (ﻏﺎﻟﺒﺎ ﺑﺎﻟﻨﺴﺒﻪ ﻻﻟﻢ ﺍﻟﺜﺪﻳﻴﻦ ﻧﺘﻴﺠﺔ ﺍﻟﻔﻄﺎﻡ یختفي ﺧﻼﻝ ﺍﺳﺒﻮﻉ ﻣﻦ ﺍﺳﺘﺨﺪﺍﻡ ﺍﻻﻗﺮﺍﺹ ﻭﺍﺫﺍ ﺗﻮﻗﻔﺖ ﺍﻻﻋﺮﺍﺽ ﻗﺒﻞ ﺍﻻﻧﺘﻬﺎﺀ ﻣن ﺍﻟﻌﻠﺒﻪ ﻳﻔﻀﻞ ﺍﻥ ﻳﻮﻗﻒ ﺍﺳﺘﺨﺪﺍﻡ ﺍﻟﻌﻘﺎﺭ) ﺟﺮﻋﺔ ﺍﻝdostinex؟؟ (لاننسی أننا قلنا ﺍﻧﻪlong acting ). ﻭﺟﺮﻋﺘﻪ ؟؟ ﻧﺺ ﻗﺮﺹ ﻣﺮﺗﻴﻦ ﻓﻲ ﺍﻻﺳﺒﻮﻉ -آلچدﻳﺮ ﺑﺎﻟﺬﻛﺮ أﻥ ﺍﻝdostinex ﻣﻤﻜﻦ وجوده ﻓﻲ وصفة ﻝmale ﻓﺄﻧﺖ ﺗﺴﺘﻐﺮﺏ لماذا؟ ﻣﻜﺘﻮﺏ ﻟﻞmale؟؟ سیکتب ل سببین -1 ﺍﻣﺎ ﺍﻝmale ﺑﻴﻌﺎﻧﻲ ﻣﻦ حالة ﺍﺳﻤﻬﺎ prolactinoma التي هي حدوث abnormally high levels of prolactin مما یؤدي ﻟﺤﺪﻭﺙ InfertilityﻭImpotence عند ﺍﻝmale *ﻣﻠاحظة ﺑﺴﻴﻄﺔ:- ﺍﻝprolactinoma تحدث أیضا ﻋﻨﺪ ﺍﻝfemale وتکون ﺳﺒﺐ ﺍﺳﺎﺳﻲ ﻟﻌﺪﻡ ﺣﺪﻭﺙ ﺍﻟﺤﻤﻞ ﻭﺑﻴﺘﻢ ﻋﻼﺟﻬﺎ ﺑﻨﻔﺲ ﺍﻟﻌﻼﺝ). -2گذلگ ﺍﺛﺒﺘﺖ ﺍﻻﺑﺤﺎﺙ ﺍﻧﻪ ﻧﺘﻴﺠﺔ لعمله ﻋﻠﻰ ﺍﻝdopamine receptors ﻭﺑﻴﻘﻠﻞ ﻣﻦ ﺍﻝprolactine ﻋﻠﻰ improve libido & ejaculation گذلگ هو یساعد علی ﺍﻝerection لذلگ قآلوا.......! cabergoline)Dostinex) has been described as....being able to do everything that Viagra can’t وآیضا ممگن تجده مکتوب في وصفة لشخص گبیر في ﺍﻟﺴﻦ ولیست وصفة نساء وعقم !!!! (السبب)... سیگون مکتوب لعلاج parkinsons Diseas الذي یکون ﻧﺘﻴﺠﺔ ﺯﻳﺎﺩﺓ ﺍﻝacetylcholine ﻓﻲ ﺍﻟﻤﺦ ﻭﻧﻘﺺ ﺍﻝ dopamine -وأخیرا... ﺍﻥ ﺍﻻﺑﺤﺎﺙ ﺍﺛﺒﺘﺖ ﺍﻥ: ﺍﻝcabergoline ﻟﻪ ﻓﺎﻋﻠﻴﻪ ﺍفضل ﻣﻦ ﺍﻝbromocriptine ﻓﻲ ﻋﻼﺝ ﻛﻞ ﺍﻟﺤﺎﻻﺕ ﺍﻟﺴﺎﺑﻘﺔ. إن شآء الله تگون قد أعجبتگم المعلومة .

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