Indications and contraindications for HRT ** indications for treatment are the following: *The symptomatic patient In the absence of any contraindications, there is very little reason not to treat a woman if symptoms are affecting her quality of life. *Premature menopause In a woman who has a menopause, either natural or iatrogenic, before 45 years, there is abundant evidence that treatment with HRT is beneficial. Thus treatment for such women is routine. *(Treatment of prevention of osteoporosis HRT is still the gold standard treatment for osteoporosis in postmenopausal women. However, in the older age group, it can be difficult to start women on HRT without side effects. *Prevention of cardiovascular disease Although previous observational studies had suggested a protective effect against heart disease, the results of the largest prospective controlled study have in fact shown an increase in the incidence of heart attacks on combined HRT. Until further studies are done, HRT is no longer indicated for the sole purpose of prevention of cardiovascular disease. **Contraindications are as follows. HRT should not be given to women with an estrogen-dependent malignant tumor. Postmenopausal bleeding or abnormal perimenopausal bleeding should be investigated before starting HRT. A history of recent or active thrombosis contraindicates HRT.
Posted on: Sat, 15 Jun 2013 18:32:29 +0000