Reviewed: January 2004 Human Chorionic Gonadotrophin (beta subunit) is used as a tumour marker for gestational trophoblastic diseases (hydatidiform moles and choriocarcinoma) and germ cell tumours of ovary or testis. As with AFP, pre-treatment ß-HCG levels are very helpful. The major clinical application is monitoring treatment response in patients with testicular tumours. It is generally recommended that follow-up samples for AFP/ß-HCG patients should be done monthly for two years post-treatment. b-HCG may also be elevated in cancers of the breast, lung, pancreas, stomach, kidney, and brain. Non-malignant elevations may be seen in bowel disease, duodenal ulcers, cirrhosis, and pregnancy. ß-HCG is a CMIA (chemiluminescent immuno-assay) on the Abbott ARCHITECT® analyzer. Samples may be serum (preferred) or plasma (heparin only). This assay measures total B-HCG and has no detectable cross-reactivity with LH, FSH, or TSH at levels of 1000 u/L of each hormone. Reference Range =
Posted on: Tue, 08 Oct 2013 21:45:14 +0000
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